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A 2023 study found that patients with cardiovascular disease who were taking semaglutide, the active ingredient in Ozempic and Wegovy, had fewer cardiovascular-related deaths and fewer heart attacks
However, glucagon also raises hepatic glucose output, which could be counterproductive in type 2 diabetes
doi:10.1111/1753-0407.12398 Lee YS & Jun HS (2014)
Interim data from REDEFINE 1 have suggested meaningful body weight reductions in adults with obesity over 68 weeks, comparing favourably with semaglutide alone
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