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Catalase and glutathione are both essential for the detoxification of hydrogen peroxide, therefor the defence of cells against H 2 O 2 ultimately and heavily depends on G-6-PD
Since even 100 M of the quinoline and artemisinin drugs hardly influenced the fluorescence ratio of isolated recombinant hGrx1-roGFP2 over 24 h, the redox effects on living cells are likely to represent real drug-induced changes
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