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D.YoungK
For example, ATP-binding cassette (ABC) transporters [e.g., P-glycoprotein (P-gp)] play an essential role in drug-related clinical resistance
Consequent covalent inhibition of H + ,K + -ATPase blocks the final step of acid secretion, hence the PPIs omeprazole, lansoprazole, and pantoprazole are more effective than histamine 2 -receptor antagonists (H 2 RAs) in controlling acid secretion
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