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The guidelines by the American Diabetes Association (ADA) and European Association for the Study of Diabetes (EASD) [13] recommend GLP-1 RA and/or sodiumglucose cotransporter 2 inhibitors (SGLT2i) for treating high-risk individuals (those with CVD and chronic kidney disease [CKD]) independent of baseline or individualized glycated hemoglobin (HbA1c) target