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These medications act on the GLP-1 receptors in the body, which are primarily located in the pancreas, intestines, and brain
For example, in Canada, attention is already shifting towards newer entrants like tirzepatide (Mounjaro/Zepbound), which has demonstrated superior efficacy in weight loss in the head-to-head SURMOUNT-5 trial iii and is gaining momentum
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Several GLP-1R agonists (GLP-1RA) have been approved to treat type 2 diabetes and have demonstrated benefits in managing obesity 16
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