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This copper-binding motif is critical: the apo-peptide (GHK without copper) shows substantially reduced biological activity in most in vitro assays, indicating that the metal center is required for receptor interaction and downstream signaling
Edited by Professor Alessandro Finazzi-Agr Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
Ghrelin and ghrelin receptor agonists stimulate gastrointestinal motility through vagal afferent pathways and direct effects on enteric neurons
Are certain people at higher risk for acetaminophen-induced glutathione depletion
