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When used alongside GLP-1 agonists, such as Ozempic, Wegovy, and Mounjaro (Calibrates doctors prescribe only GLP-1s due to the stronger evidence base for these drugs), a real-world cohort of over 2,500 members achieved an average 15% weight loss, exceeding the use of these drugs alone

Physical activity, dietary factors, and behavioral interventions could plausibly explain sustained weight loss in a subset of patients and must be incorporated into future analyses

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