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The association of the variant GPX4 genotypes with the increased risk of CS in hypertensives remained statistically significant after adjusting for confounding variables such as sex, body mass index (BMI), blood pressure and antihypertensive medication use (OR=2.18, 95%CI 1.463.27, P =0.0015)
However, people with kidney disease, liver disease, seizure disorders, thyroid conditions, cardiovascular disease, pregnancy, breastfeeding, cancer history or prescription medication use should speak with a healthcare professional before supplementing
Kannt A et al