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Immunofluorescence staining also showed a marked increase in the number of Ki-67-positive cells and a decrease in the nuclear content of -H2AX and P21 after FOXO4-DRI treatment (Figures 4B,C)
Formation of new blood vessels (angiogenesis) via VEGFR2 The best-documented pathway
In cartilage, chronic inflammation drives osteoarthritis progression destroying matrix faster than chondrocytes can rebuild
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