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Gastric bypass surgery recruits a gut PPAR--striatal D1R pathway to reduce fat appetite in obese rats

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The primary role of mTORC1 is to integrate signals from growth factors and nutrients to drive cellular growth, under conditions of energy abundance or nutrient-scarcity-triggered catabolism

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Jing F, Zou Q, Wang Y, Cai Z, Tang Y (2021) Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation

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They suggest that this potential side-effect should be taken into account by clinicians when deciding on treatments for patients with obesity or type 2 diabetes

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