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Supports cellular function

The cAMP/PKA pathway inhibits voltage-gated potassium channels that respond to depolarization, opens and allows K + efflux, repolarizing the cell and allowing increased calcium influx through voltage-dependent calcium channels, resulting in the exocytosis of insulin from -cells (115)

Metabolic Roles L-arginine Semi-essential amino acid Direct precursor to nitric oxide Involved in protein synthesis and hormone secretion functions L-citrulline Non-essential amino acid Converted to L-arginine in the kidneys Involved in the urea cycle Absorption and Bioavailability L-citrulline has been shown to have an advantage over L-arginine in terms of absorption and bioavailability: L-citrulline is noted as being efficiently absorbed by the intestines