does glp-1 boost work Science Behind GLP 1 GIP and Glucagon Receptor Agonists for Obesity Research | News & Announcements GLP-1 | Summary

Adverse Reactions/Side Effects The following important adverse reactions are described below and elsewhere in the labeling: Lactic Acidosis [see Boxed Warning and Warnings and Precautions (5.1)] Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus and Other Ketoacidosis [see Warnings and Precautions (5.2)] Volume Depletion [see Warnings and Precautions (5.3)] Genitourinary Infections, including Urosepsis, Pyelonephritis, Necrotizing Fasciitis of the Perineum (Fournier's Gangrene), and Genital Mycotic Infections [see Warnings and Precautions (5.4)] Hypoglycemia [see Warnings and Precautions (5.5)] Lower Limb Amputation [see Warnings and Precautions (5.6)] Hypersensitivity Reactions [see Warnings and Precautions (5.7)] Vitamin B12 Deficiency [see Warnings and Precautions (5.8)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

It is entirely possible that the slight rise in optic nerve issues reflects the underlying, advanced vascular damage or high baseline cardiovascular strains already present in patients who require these stronger medications, rather than a direct toxic effect of the drug molecules themselves

Lipparini, F

Liver Int 31 , 12851297, (2011)