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While it has been postulated that these two actions are inextricably linked more recent data shows they can indeed be divorced which opens the opportunity for tailored pharmacology that provide food intake reduction without the adverse events typically associated with GLP-1R agonism

The GLP-1 medication semaglutide has been shown to be effective and safe across a broad population of people with overweight and obesity, leading to 10-20% weight loss which is usually needed to see the benefits

If youre ready to explore this transition, TrimRxs intake quiz can connect you with a provider who manages semaglutide-to-tirzepatide switches regularly and can build a personalized titration plan based on your treatment history

Some people get a little lightheaded, especially if they haven't eaten recently