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FIGUR 5 Results of measurement of area percentage positive SIRT -1 reaction in hepatic tissue The APAP group showed a significant decrease in the percentage of SIRT1 positive reaction when compared to the control group ( p -value 0.001)
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Therefore, they speculated that caffeic acid probably acts as a major player in the preventive effect of chlorogenic acid against oxidative damage in ischemiareperfusion intestinal tissue [170]
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