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If cholelithiasis is suspected, gallbladder studies and appropriate clinical follow-up are indicated Hypoglycemia: Adult patients with type 2 diabetes on an insulin secretagogue (eg, a sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia with use of Saxenda

Dulling the sugar rush GLP-1s affect the brains reward system, which is responsible for motivation and desire, so its not surprising they can impact other impulses beyond food

GLP-1 agonists, through their effects on insulin secretion, glucagon suppression, and gastric emptying, are particularly effective at controlling post-meal glucose excursions

Injection does not change the body's downstream carnitine metabolism, so the TMA/TMAO pathway applies regardless of route