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Methods Computer-aided molecular design, synthesis, and characterization All the computer-aided molecular design studies were performed in SZMAP/GamePlan 37 and vBrood 38 modules in OpenEye software and Molecular Operating Environment, MOE 39

[8] : 155165 Vitamin C was discovered in 1912, isolated in 1928, and in 1933, was the first vitamin to be chemically produced

doi:10.1001/jama.2023.24945 Busetto L, Bettini S, Makaronidis J, Roberts CA, Halford JCG, Batterham RL