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doi: 10.3389/fphar.2023.1122632 Received 13 December 2022 Accepted 13 March 2023 Published 27 March 2023 Volume 14 - 2023 Edited by Enrico Sangiovanni, University of Milan, Italy Reviewed by Ayaz Shahid, Western University of Health Sciences, United States Andres A
Rather than slowing gastric emptying or mimicking incretin hormones, tesofensine directly modulates central nervous system neurochemistry to influence appetite, satiety signaling, and energy expenditure
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[2] In combination, these effects can result in significant weight loss in overweight and obese individuals
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