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The weekly GLP-1 receptor agonist (GLP-1 RA) diabetes medication has been in short supply since April, in large part due to its promotion as a weight loss drug on social media platforms like TikTok

Clinical trial data suggests comparable GI side effect profiles, though some patients who cannot tolerate one medication do better on the other due to individual receptor sensitivity differences

They assess your current condition, and previous medical records and create a customized treatment plan to ensure a smooth transition from semaglutide to tirzepatide with minimum side effects

New Engl J Med (2021) 384(11):9891002