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Digoxin: Sitagliptin had a minimal effect on the pharmacokinetics of digoxin

La hiperglucemia crnica (a travs de la inflamacin y de productos fina les de glicosilacin avanzada) as como la obesidad, la dislipidemia, la hiperuricemia y la hipertensin arterial no controlada, que acompaan frecuentemente a la DM2, contribuyen al dao renal 12

Combined anabolic and micronutrient vulnerabilities in these populations may influence musculoskeletal resilience

If any of these combinations can demonstrate that muscle preservation leads to better long-term weight maintenance, reduced metabolic complications, and improved functional outcomes, it could become the new standard of care alongside GLP-1 therapy