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Plasma concentrations decline substantially with age, which forms the basis of most regenerative hypotheses about it
Primary applications: wound healing (closure kinetics, collagen organization, tensile strength), tendon and ligament regeneration (Achilles transection, biomechanical testing), gastroprotection (NSAID protection, mucosal barrier, fistula healing), angiogenesis (HUVEC tube formation, VEGF expression, CAM assays), neuroprotection (gut-brain axis, neuroinflammatory reduction), and inflammation studies (cytokine modulation, ERK1/2 pathway)
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