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Gene expression studies confirm direct effects on pathways controlling hair growth, and the combination of preclinical efficacy plus clinical success in topical applications supports the rationale for injectable use
ALCAR downregulates pro-inflammatory cytokine/chemokine involved in PCa and BPH cells Evidence from the clinic indicates that prostate cancer progression correlates with elevated inflammation [3, 8,9,10,11, 37, 38]
On the contrary, these metabolites were not produced by the rats receiving the isotope intravenously and germ-free rats receiving the tracer orally, suggesting that orally ingested LC is in part degraded by the guts microorganisms [55]
Therefore, the mechanisms of EA should not be viewed in isolation
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