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2014 Dec;171(24):5696-707
In this context , laboratory models allow researchers to analyze how biological systems maintain structural organization, cellular communication, and adaptive balance under controlled conditions
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The result is selective apoptosis of FOXO4-high senescent cells, leaving FOXO4-low non-senescent cells intact a selectivity that makes it a uniquely powerful molecular probe for studying the contribution of senescent cell accumulation to tissue dysfunction, ageing phenotypes, and disease biology
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