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The blood-brain barrier obstacle The BBB is a selective semipermeable interface between neuronal tissue and blood vessels that form the neurovascular unit, with the main role of helping normal brain homeostasis, regulating influx and efflux transport, and ensure protection, mediating the communication between CNS and peripheral one (Rhea and Banks, 2019)

Real-world safety depends on dose, route of administration, baseline health status, and individual genetic variation

Hence, due to the controversial evidence, exploring the molecular regulation of GPx1 expression and activity is very important for understanding the mechanisms of cancers

L.) 309327 (Elsevier, 2020)