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The differences between groups were calculated by Wilcoxon rank sum test (non-parametric statistics)

Cardiovascular Safety Studies With DPP-4 Inhibitors The Clinical Guidance for Pharmaceutical IndustryDiabetes MellitusEvaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes established by the FDA in 2008 as a consequence of adverse safety signals of rosiglitazone has set up the requirement for novel diabetes medications to prove cardiovascular safety of these substances in comparison to standard therapy under glycaemic equipoise

Helps restore elasticity and improve skin texture on the face, neck, arms, and abdomen

Adjusting antihypertensive doses early often prevents this issue