The full primary sequence, as published in the Sikiric laboratory's foundational work and reproduced across subsequent literature, is: Sequence (one-letter): GEPPPGKPADDAGLV Sequence (three-letter): Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Length: 15 amino acids (pentadecapeptide) Molecular weight: 1419.5 Da (monoisotopic) Molecular formula: C 62 H 98 N 16 O 22 Designation: "BPC" = Body Protection Compound
KD treatment in patients with DKD resulted in more significant reductions in waist circumference, lean body mass, eGFR, as well as levels of insulin, HbA1c, fasting blood glucose, LDL-C, and IL-6 compared to those following a low-protein, low-salt diet, with modest increases in HDL-C and LDL-C levels [121]
Boiling may lead to greater losses, while steaming or lightly cooking vegetables may help preserve more of their beneficial nutrients and antioxidants
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, et al