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TB-500 is a fragment of the full-length thymosin beta-4 (43 amino acids), and the full-length TB-4 has substantially more human safety data than the fragment
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Theoretical considerations suggest fat loss effects should continue as long as the compound is administered, since the mechanism (beta-3 adrenergic lipolysis, lipogenesis inhibition) does not involve receptor desensitization in the way that some hormonal pathways do
Thus, a higher Bcl-2/Bax ratio is posted as a predominance of Bcl-2, which may inhibit apoptosis and apparently promotes cell survival
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