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Among the intestinal L cell peptides, glucagon-like peptide-1 (GLP-1) has been highlighted because of the success of its recent clinical use in the treatment of diabetes mellitus and obesity [2]
Whilst Ozempic does not typically cause cognitive impairment, hypoglycaemia (if it occurs, particularly in patients also taking insulin or sulphonylureas) can affect mental function
Approaching maximum dose
Studies in rats suggest that berberine increases GLP-1 secretion
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