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Weight loss plateaus are common as the body adapts to reduced calorie intake and lower body weight

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Energy and sleep improvements often come first, within the initial 46 weeks

97 have shown that 1040% CR over 3 months in C57BL/6 mice (corresponding to approximately a tenth of their lifespan) decreases blood glucose, insulin and IGF-1 concentrations, the latter showing the greatest dependence upon the severity of CR

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