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Wt animals exhibited a single pulse whose dynamics returned to the basal level (exact adaptation), while tax6 mutants responded with a single pulse that was higher in amplitude and which remained above basal level for as long as the stimulus remained on

2 13 In type 2 diabetes trials, cagrilintide added to semaglutide improved glycemic control beyond semaglutide alone, consistent with a real postprandial contribution though because it was studied in combination, the cagrilintide-specific share cannot be cleanly separated