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Observed effects include increased histone acetylation and decreased DNA methylation, which have been linked to meiotic irregularities and aneuploidy susceptibility [337,338,339]
Dating as far back as the 1930s, this system has been implicated in appetite suppression and weight loss due to its targeting by amphetamines [89], which has been confirmed by contemporary neuroscience techniques
Nature Communications , 14 , 2692
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