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10.2337/db16-1009 Summary Keywords GLP-1 receptor agonist, molecular mechanisms, gut microbiota, multi-organ protection, therapeutic repurposing Citation Gong B, Li C, Shi Z, Wang F, Dai R, Chen G and Su H (2025) GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy

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Unlike some medications, GLP-1 agonists like semaglutide and tirzepatide do not require a medically mandatory taper there is no withdrawal syndrome or physical dependence risk in the traditional sense