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Receptor-ligand interactions are crucial for cell signalling
20 Primarily, NADPH provides reducing equivalents for fatty acid synthase (FASN), the main rate-limiting enzyme, to synthesize fatty acids with acetyl-CoA serving as a primer and malonyl-CoA as a two-carbon donor, 21,22 and provides the needed electrons for ironsulfur (Fe/S) protein assembly that participate in non-essential amino acid biosynthesis and lipoic acid synthesis, tRNA modification, DNA replication and repair, and telomere maintenance
Its primary role includes regulating blood sugar levels by influencing insulin secretion, appetite, and digestion
Mitochondrial dynamics impacts stem cell identity and fate decisions by regulating a nuclear transcriptional program, Cell Stem Cell 19, 232247
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