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A recent study further demonstrated that smoking increased the risk of ALD, cirrhosis, and HCC by 1.32-, 1.53-, and 1.53-fold, respectively (all p 1 pack/day), is associated with elevated alanine aminotransferase (ALT) levels in HCV antibody-positive patients [16]

[44] [45] There is a tremendous diversity of individual P-450 gene products, and this heterogeneity allows the liver to perform oxidation on a vast array of chemicals (including most drugs) in phase 1

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