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Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control
Appetite stimulation is a plausible on-target effect because GHSR-1a is also the receptor for ghrelin, a hunger-signaling hormone
Archived from the original on August 21, 2022
2-HG has been demonstrated to inhibit histone demethylation, specifically the Jumonji family histone lysine demethylase KDM4C, thereby impairing the expression of genes important in normal cellular differentiation (27)
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