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6.3 Metabolites and ASMs Women with epilepsy treated with lamotrigine monotherapy showed a trend toward higher circulating 3-hydroxy-5/-reduced androstane levels (148)

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In the STZ-induced diabetic mouse model, DNA synthesis increases and peaks at day 2 in the proximal tubules, and the expression of various growth factors including epidermal growth factor (EGF), platelet-derived growth factor (PDGF), basic fibroblast growth factor (FGF), insulin-like growth factor-1 (IGF-1), hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) has been observed ( Figure 1 )

Individual variation: Results differ greatly from person to person