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Moreover, last year a separate study showed that 91% of obese individuals receiving a weekly dose of 15 mg Tirzepatidea recently developed GLP-1R/GIPR dual agonist, lost 5% of their body mass with 36% of participants on the same dosage losing at least 25% ( While these data are astoundingwith yearly progress in efficacy, we should consider that around 9% of patients receiving these game-changer treatments (Table 1)

For people on higher dose protocols, the 10mg protocol and the considerations around higher unit doses are relevant, since higher doses tend to produce stronger side effect profiles, particularly in the first 24 to 48 hours post-injection

Q: Whats the trajectory of GLP-1 use in the UK and globally