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Women of reproductive age are particularly vulnerable
The study showed that participants in the weight loss intervention who achieved an average weight loss of 6.6kg compared to 1.1kg in the control group had higher pregnancy rates (48% vs 14%), live birth rates (44% vs 14%), and fewer cycles of IVF to pregnancy (two vs four) compared to the control group
In addition, in a pig model, Lactobacillus reuteri XL0930 in the gut microbiota reduced muscle carnitine levels and promoted fatty acid deposition by downregulating SLC22A5 in muscle tissue [253]
Trulicity, in contrast, is available in primary care as part of routine diabetes management
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