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Consequently, the targeted regulation of iron ion homeostasis has emerged as an effective strategy for the prevention and treatment of numerous major diseases, with new clinical pharmacological agents being widely implemented [7]
Over the ensuing 25 years, endogenous neurosteroids have been implicated in learning and memory function, hippocampal information processes, and synaptic plasticity (48, 5963)
Absence of sedation is verified by locomotor activity (distance travelled) and rotarod tests for motor coordination
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