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GIP receptor activation Glucose-dependent insulinotropic polypeptide (GIP) is the second receptor target, similar to tirzepatide (Mounjaro, Zepbound): Effects: Enhances insulin release from the pancreas Works synergistically with GLP-1 for appetite control May influence fat storage and energy balance Improves glucose regulation Tirzepatide's success as a dual GLP-1/GIP agonist demonstrated that adding GIP to GLP-1 enhances weight loss beyond GLP-1 alone
Anthony Collova , Founder, IIFYM.com 15+ years coaching macro tracking & fat loss ~14 min Medical disclaimer: This article is for educational purposes only and isn't medical advice
Diabetes 53: 13261335
With a large diabetic and pre-diabetic population, GLP-1 therapies are gaining acceptance as dual-purpose treatments
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