how many b12 injections per week Injection Dosage and Frequency: 7 Guidelines for Adults Best Vitamin B12 Injection Dose

While not toxic, excessively high doses are usually unnecessary

Chandys hypothesis, that the rapid onset of the repairing processes induced by B12 shots might overwhelm the system and temporarily cause a worsening in symptoms, similar to the Jarisch-Herxheimer reaction in those treated for Lyme disease

Strength of evidence: Anecdotal reports, rodent studies, and Phase 2 human trials all carry different weight

Documentation requirements for J3420 claims Medicare audits for J-code injectable drug claims, and vitamin B12 injections are a recurring area of scrutiny because of the high volume of wellness injections administered without documented medical necessity