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Epithalon functions as an epigenetic modulator, interacting directly with the genome rather than cell surface receptors
3.1.1 Preclinical evidence Administration of metformin before ischemia or at reperfusion reduces myocardial injury in diabetic and non-diabetic models without altering blood glucose
Diabetes 59(Suppl 1):611-P, Abstract Thomas C, Gioiello A, Noriega L et al (2009) TGR5-mediated bile acid sensing controls glucose homeostasis
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