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Option (Evidence Strength: Grade C) A trial of neuromodulation may be performed if other treatments have not provided adequate symptom control and quality of life improvement
Tesofensine acts on the brains monoamine systems (dopamine, norepinephrine, serotonin reuptake) supplied for laboratory research use only
This trial suggests that a 12-week course of probiotic supplementation resulted in beneficial effects on both movement and other selected metabolic factors in individuals with PD (160)
10.1073/pnas.1809548115 45 SarkarM.KushnerT
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