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Key findings included: Semaglutide improved all outcome measures in patients with heart failure (MACE HR 0.72, cardiovascular death HR 0.76, all-cause mortality HR 0.81), compared with those without heart failure

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Additionally, in the trial examining alcohol use disorder, a significant reduction in alcohol consumption was observed only in a specific subgroup of patients with obesity, suggesting that patient characteristics, such as BMI, might influence treatment outcomes