Vukojevic, V., Sikiric, P., Seiwerth, S., Petrovic, I., Marovic, A., Drmic, D., & Staresinic, M
It is found in large quantities in many cells in the body (1-10 millimoles/L)
HSYA reduces LDH content and caspase-3 expression, alleviates oxidative stress and apoptosis, and increases ATP production and mitochondrial energy metabolism in H/R-induced H9C2 cells, potentially by targeting and modulating the Akt/HKII signaling pathway
Clinical Trial Findings: Quantification of Cytokines IFN-, TNF-, IL-2, and IL-10 Levels in Plasma and PBMCs From T2DM Subjects Levels of cytokines IFN-, TNF-, IL-2, and IL-10 were quantified in plasma and PBMCs isolated from T2DM subjects at pre- and post- L-GSH/or placebo supplementation