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PNT directly suppresses T cell functionality by nitrating their T cell receptors (TCRs), diminishing their responsiveness to MHC-antigen complexes [26]

Note: Each user should empirically determine the optimal amount of beads to be used based on the amount of the biotinylated molecules in the crude sample

NRF2 then dimerizes with members of the sMaf proteins through its bZIP domains and binds to the ARE sequences, which are regulatory enhancers, within gene promoters [156, 161]

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