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Amgen Decision The Patent Dance is the informal name for the BPCIAs multi-step, timed information exchange process between a biosimilar applicant and the reference product sponsor (RPS)

14 A 2017 meta-analysis of 52 randomized, controlled trials that evaluated DPP-4 inhibitors' effects on beta-cell function found that, in monotherapy studies, all agents except linagliptin resulted in improvements in cell function