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The GLP-1 component of tirzepatide slows gastric emptying and triggers satiety signals in the hypothalamus, while the GIP component enhances insulin secretion and may improve metabolic flexibility
After reconstitution, refrigerate for short-term stability
Therefore, the metabolic adaptations observed here probably occurred in the background of the recently identified glucose-induced transcriptional program
Those with heart or kidney disease should follow their healthcare provider's specific advice about fluid intake
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