semaglutide and ibs-d Why Constipation Matters While on GLP-1/GIP-1 Medications Constipation is a common sometimes underappreciated side effect of GLP-1 and GIP-1 agonists like (Wegovy®) or tirzepatide (Zepbound®). Left untreated, it can lead Gastrointestinal symptoms, including nausea, vomiting,
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