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As of 2024, IgG Fc engineering as a strategy to prolong plasma half-life is used in approved therapeutics for diverse pathologies, including for instance neutralization of a virus (YTE containing
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10.1016/j.clnesp.2018.04.002 Clin
Preclinical research indicates that NNMT inhibition may influence adipose tissue function, mitochondrial efficiency, and intracellular energy utilization through mechanisms distinct from traditional endocrine or appetite-regulating pathways
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