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Some clinicians are prescribing tirzepatide to breastfeeding mothers based on its molecular similarity to GLP-1, its large molecular weight (which reduces breast milk transfer), and the favorable animal data
Sermorelin Sermorelin, the synthetic version of naturally occurring growth hormone-releasing hormone (GHRH), has been gaining some attention as an alternative to weight loss injectables like Mounjaro and Wegovy
Reducing from 50 units to 40 units (4.0 mg at 10 mg/mL) or even 35 units (3.5 mg) can dramatically improve tolerability while maintaining meaningful therapeutic effect
It produces a pulse of growth hormone and has a relatively short half-life
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